February 9, , by NCI Staff. Researchers are developing tumor-targeting viruses, like this engineered poliovirus, as potential cancer treatments. For more than a century, doctors have been interested in using viruses to treat cancer, and in recent years a small but growing number of patients have begun to benefit from this approach. Some viruses tend to infect and kill tumor cells. Known as oncolytic viruses , this group includes viruses found in nature as well as viruses modified in the laboratory to reproduce efficiently in cancer cells without harming healthy cells. To date, only one oncolytic virus— a genetically modified form of a herpesvirus for treating melanoma —has been approved by the Food and Drug Administration FDA , though a number of viruses are being evaluated as potential treatments for cancer in clinical trials.
EXCLUSIVE: Cold sores are KEY to destroying cancer tumours
Common cold virus may be new weapon to fight cancer | Cancer research | The Guardian
An oncolytic virus is a virus that preferentially infects and kills cancer cells. As the infected cancer cells are destroyed by oncolysis , they release new infectious virus particles or virions to help destroy the remaining tumour. The potential of viruses as anti-cancer agents was first realised in the early twentieth century, although coordinated research efforts did not begin until the s. The first oncolytic virus to be approved by a national regulatory agency was genetically unmodified ECHO-7 strain enterovirus RIGVIR , which was approved in Latvia in for the treatment of skin melanoma ;  the approval was withdrawn in An oncolytic adenovirus , a genetically modified adenovirus named H , was approved in China in for the treatment of head and neck cancer. A connection between cancer regression and viruses has long been theorised, and case reports of regression noted in cervical cancer , Burkitt lymphoma , and Hodgkin lymphoma , after immunisation or infection with an unrelated virus appeared at the beginning of the 20th century.
Common cold virus may be new weapon to fight cancer
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The death rate from cancer in the United States has continued to decline. This includes a 2. Cancer patients, their caregivers, and others need to take precautions to lower their risk of getting COVID Learn some basic facts about what you can do to help protect yourself and others. A study using data from the Centers for Disease Control and Prevention CDC provides evidence that the human papillomavirus HPV vaccine is effectively reducing the numbers of cervical precancer — lesions that can become cervical cancer.